štvrtok 3. septembra 2009

stable CAD: BARI 2D: No difference in mortality, CVD: revascularisation vs medical therapy, COURAGE

BARI 2D in Type 2 diabetics n=2000+ pts
FU 5 years
treated with revascularisation (CABG or PCI) or intensive medical therapy.
no difference between revasc vs medical therapy
lower MI in CABG
no benefit of PCI

cf analogous to results of the COURAGE trial

- second randomization strategy
insulin provision vs senzitization.

best outcome in CABG+insulin senzitization .(least prone to hypo?)

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